منابع مشابه
Chemical carcinogenesis.
The use of chemical compounds benefits society in a number of ways. Pesticides, for instance, enable foodstuffs to be produced in sufficient quantities to satisfy the needs of millions of people, a condition that has led to an increase in levels of life expectancy. Yet, at times, these benefits are offset by certain disadvantages, notably the toxic side effects of the chemical compounds used. E...
متن کاملMechanisms of Chemical Carcinogenesis
a very interesting model for both Dandhoff disease and Tay-Sachs disease in the human. The fourth section includes papers discussing inborn errors of connective and epidermal tissues in animals. Direct analogy to the human is more difficult in these particular models; however, there is one model that is somewhat similar to osteogenesis imperfecta. Brown's paper discussing inborn errors of carti...
متن کاملEnvironmental and chemical carcinogenesis.
People are continuously exposed exogenously to varying amounts of chemicals that have been shown to have carcinogenic or mutagenic properties in experimental systems. Exposure can occur exogenously when these agents are present in food, air or water, and also endogenously when they are products of metabolism or pathophysiologic states such as inflammation. It has been estimated that exposure to...
متن کاملThresholds in chemical carcinogenesis.
It is common practice to base carcinogenic risk assessment on the view that there is no threshold for chemical carcinogenesis. In this context, the threshold is defined as a dose below which no effects are observed. Analysis of epidemiological and experimental data on chemical carcinogenesis confirms that no thresholds have been demonstrated in human or animal studies, including the ED01 study ...
متن کاملChemical carcinogenesis; a review.
Chenistry of Carcinogenic Compounds The first of the eighteen articles, which is by Haddow and Kon, on the chemistry of carcinogenic compounds1 begins with Percival Pott (1775) and leads the history of the subject via Yamagiwa to Kennaway's work on synthetic tars (Kennaway, 1924, 1925; Kennaway and Hieger,. 1930) and his discoveryt of the first cancer producing hydrocarbon, I: 2: 5: 6-dibenzant...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 1978
ISSN: 1460-2105,0027-8874
DOI: 10.1093/jnci/60.1.11